Milla Jovovich Alice Oded Fehr Carlos Olivera Ali Larter Claire Redfield Iain Glen Dr. Isaacs Ashanti Betty Christopher Egan Mikey Spencer Locke K-Mart Matthew Marsden Slater Linden Ashby Chaser Jason O'Mara Albert Wesker Mike Epps L.J. Joe Hursley Otto James Tumminia Lab Tech Madeline Carroll White Queen Valorie Hubbard Ma Carrie Eklund Camp Survivor (uncredited) Brian Steele Rancid / Tyrant John Eric Bentley Umbrella Tech Kirk B.R. Woller Scientist Rick Cramer Ice Hockey / Corridor Guard Peter O'Meara British Envoy William Abadie French Envoy Ramón Franco Runty Shane Woodson Piggy Geoff Meed Pock Mark Rusty Joiner Eddie Carolina Jiménez Mirror Woman Gary A. Hecker Tyrant Vocal (voice) Martin Crewes Chad Kaplan (uncredited) Richard Epcar Additional Voices (voice) (uncredited) Stefen Hayes Yuri Loginova (uncredited) Gary Hudson Umbrella Captain (uncredited) Ryan McCluskey Mr. Grey (uncredited) Carsten Norgaard Zombie Steve (uncredited) César Ámigo Aguilar Foreign Envoy (uncredited)