Megan Fox April O'Neil Will Arnett Vernon Fenwick William Fichtner Eric Sacks Danny Woodburn Master Splinter Abby Elliott Taylor Noel Fisher Michelangelo Jeremy Howard Donatello Pete Ploszek Leonardo Alan Ritchson Raphael Johnny Knoxville Leonardo (voice) Tony Shalhoub Splinter (voice) Tohoru Masamune Shredder Whoopi Goldberg Bernadette Thompson Minae Noji Karai Madison Mason Councilman Derek Mears Dojo Ninja Malina Weissman Young April O'Neil Taran Killam McNaughton K. Todd Freeman Dr. Baxter Stockman Paul Fitzgerald Dr. O'Neil Venida Evans Subway Hostage Mikal Vega Sacks Bodyguard Chance Kelly Mr. Rivetti